Historical Newspapers of South Carolina

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Profe, BY MARK M( ItUOW H1E WORKS in a small office in the Biology building surrounded by microscopes, file cabinets and notebooks of data. On his desk are piles of letters, notes and a stack of tests from his Biology 620 class. His graduate student, Rob Allen, works behind him peering through the lens of a microscope at some cancer cells they are studying. A half-opened window allows some cool air to circulate in the small room where Dr. Gerald J. Miez jewski does his research with liver cancer (h1'atona s). Miezjew%.- i has been working with liver cancer for the past two years in an effort to answer some of the questions that surround the disease. Cancer kills thousands each year and liver cancer is one of the more lethal forms of cancer. Once it has been detected it is usually too late to treat effectively. Miezjewski said his research is RED SJ CLJ RACHMANINOFF THE DELLS ne" FRANCK SYMPHONY IN 0 MINOR MUNCH BOSTON SYMPHONY *0 DL 10 ssor Do, "very young" and in the present stage they are learning all they can about the tumor itself. M1IEZ.IEWSKI said his work is based on an animal model of liver cancer. It is transplanted into mice and in 30 days he will have a well developed tumor to study. Miezjewski said he is studying the traits and character of the tumor in order "to get to know the tumor better." The professor and his collegues are studying the biological changes of the host, the chromosomes, the lipids and protein content hoping to find out what makes the tumor grow. The wok is contained in three branches, Miezjewski said. One stage, the embryonic aspect, studies the fetal characteristics of the tumor. Miezjewski and a graduate student are studying the liver of the fetus to determine how similar the tumor is to the developing fetus. In another branch of his work, he is studying EAL & VI LSSICAL All RCA Red Seal Classics pl all RCA Victrola Budget Classi, are specially priced at the Reco Bar this week. ALL S5.98 LIST RCA CLAS! NOW ONLY S3.99 ALL S2.98 LIST RCA CLAS5 NOW ONLY $1.98 ALLS6.98 LIST RCA TAPE NOW ONLY S5.29 1.SALE LASTS FEB. 18-23 nCn RE OSr At LEONTYNE PRICE Puccini Heroines La Bohemei MadamajButie-i, in.a Manion Ieaaui La Ijnou" Jde We LaRoandine ieV idg New Ph,?tann lOL. O,(iestra EDWARD DOWNE S cord iTCH SQL -9.30 mon ing Can the bio-chemistry of the tumor. Miezjewski said he also wants to find out how the host reacts to the presence of the tumor. He hopes to find the defense mechanisms of the animal and then devise im Inu'lothera peutic devices to attack the cancer. In tne third branch of his research, he has a graduate student working with the physiological aspects of the tumor trying to determine the function of molecules that the tumor produces. A'CORDING TO Miezjewski, the hepatoma is highly antigenic (antigen producing) type of cancer and he has designed his ex periments around that fact. lie said the animal produces an tibodies that go to the tumor and collect around it. When he removes a tumor, the antibodies no longer have a target tissue and accumulate in the body. These antibodies are useful in his studies because it is part of the animal's vTROLA SALE Rn/n RED SEAL us C UQ T C[T cs [)VOPC(k rd ICS nCR RED SEAL Efff (I'Vft.4N[) QUAI1ILI n1 C. - TCHAIKOVSKY SYMPHONY NO 4 MUNCH BOSTON SYMPHONY EBar FARE .-sat. cer Res natural defense. The tumor Miezjewski works with originated in a mouse in Bar Harbor, Maine in 1958. He said the tumor has been maintained by serial transplant since then. He brought the tumor here in 1972 and it has gone through 24 transplants. Miezjewski takes the tumor out of one mouse, dices it up and puts it into the bodies of other animals. One of the main problems in tumor immunology, according to Miezjewski, is finding something that is specific to the tumor and nothing else. "The ideal would be to find some substance that will disperse the tumor and then have the antibodies attack each cell individually," Miezjewski said. However, he said they were a long way from that stage. MIEZ.JEWSKI HAS selected a product that is secreted by the tumor and is studying it. The product, alpha-fetoprotein, is related in some way to the growth rate of the tumor, Miezjewski said, and is also related to the hormonal balance of the tumor. The serum has been used recently as a screening tool to diagnose cancer since the amount of the chemical present increases significantly with the presence of liver cancer in humans. Garnet Ano Undergoes BY LISA GARDNER Carolina students will be getting eight bound magazines for the price of one yearbook when the Garnet and Black is distributed in April, editor Randy Newcome says. Accurding to Newcome, the cover of the yearbook will look like that of any traditional college annual. The magazines, facimiles of eight popular publications, will be bound inside the cover by screws. "Every person will be able to change the format of his yearbook. By removing the screws he can change the order of the magazines or even throw a magazine away if he doesn't like it," Newcome says. The magazines that the Garnet and Black staff imitated are 'Intellectual Digest," "Ms," "National Lampoon," "Playboy,'' ''Sturay Evening Post,'' "SatrdayReview of the Arts.'' Jim (Gr lii,aun in, I<'. R-. ASI/ 9 .1 Barch Dr. Miezjeu-ski ...cancer researcher. I Black Change 'Southern Living, and "Sports Illustrated." Each magazine was hosen for its theme aind its idaptability to a particular phase Af campus life. "Southcrn Living'.' for example , covers issues in student life such as parking, construction on campus and pre registration. "The game we're playing is to pretend that the staffs from these magazines came to cover Carolina. We've tried to mimic their writing style, their layout, everything. "Playboy will have an interview and a centerfold. The model isn't nude but the pose is the most in teresting view of the playmate we could print. "National Lampoon" has 16 pages of artwork and it's all humor. Copies ot the Garnet and Black can still he ordered. For in formation (all the (;arnet and Black office at 4170. N A I LS Il'urt/ ( ('eter ( 1, I 'r